Detrimental Effects of Ethanol and Its Metabolite Acetaldehyde, on First Trimester Human Placental Cell Turnover and Function

Sylvia Lui; Rebecca L. Jones; Nathalie J. Robinson; Susan L. Greenwood; John D. Aplin; Clare L. Tower

doi:10.1371/journal.pone.0087328

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Peer-reviewed

Research Article

Detrimental Effects of Ethanol and Its Metabolite Acetaldehyde, on First Trimester Human Placental Cell Turnover and Function

Sylvia Lui ,

* E-mail: sylvia.lui@manchester.ac.uk

Affiliation Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom
⨯
Rebecca L. Jones,

Affiliations Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Nathalie J. Robinson,

Affiliations Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Susan L. Greenwood,

Affiliations Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
John D. Aplin,

Affiliations Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Clare L. Tower

Affiliations Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, St. Mary’s Hospital, Manchester, United Kingdom, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯

Detrimental Effects of Ethanol and Its Metabolite Acetaldehyde, on First Trimester Human Placental Cell Turnover and Function

Sylvia Lui,
Rebecca L. Jones,
Nathalie J. Robinson,
Susan L. Greenwood,
John D. Aplin,
Clare L. Tower

x

Published: February 4, 2014
https://doi.org/10.1371/journal.pone.0087328

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Acetaldehyde
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Ethanol
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Pregnancy
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Alcohol consumption
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Placenta
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Apoptosis
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Trophoblasts
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Blood
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