Combinatorial PD-1 Blockade and CD137 Activation Has Therapeutic Efficacy in Murine Cancer Models and Synergizes with Cisplatin

• Huafeng Wei ,

  Contributed equally to this work with: Huafeng Wei, Likun Zhao

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Likun Zhao ,

  Contributed equally to this work with: Huafeng Wei, Likun Zhao

  Affiliation School of Bioscience and Bioengneering, South China University of Technology, Guangzhou, China

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• Wei Li,

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Kexing Fan,

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Weizhu Qian,

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Sheng Hou,

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Hao Wang,

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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• Min Dai,

  Affiliation Department of Pathology, Harborview Medical Center, University of Washington, Seattle, Washington, United States of America

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• Ingegerd Hellstrom,

  Affiliation Department of Pathology, Harborview Medical Center, University of Washington, Seattle, Washington, United States of America

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• Karl Erik Hellstrom,

  Affiliation Department of Pathology, Harborview Medical Center, University of Washington, Seattle, Washington, United States of America

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• Yajun Guo

  * E-mail: yguo_smmu@163.com

  Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, School of Bioscience and Bioengneering, South China University of Technology, Guangzhou, China, School of Pharmacy, Liaocheng University, Liaocheng, China

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