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Disulfiram Eradicates Tumor-Initiating Hepatocellular Carcinoma Cells in ROS-p38 MAPK Pathway-Dependent and -Independent Manners

  • Tetsuhiro Chiba ,

    Contributed equally to this work with: Tetsuhiro Chiba, Eiichiro Suzuki

    techiba@faculty.chiba-u.jp

    Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Eiichiro Suzuki ,

    Contributed equally to this work with: Tetsuhiro Chiba, Eiichiro Suzuki

    Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Kaori Yuki,

    Affiliations Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan, Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Yoh Zen,

    Affiliation Institute of Liver Studies, King's College Hospital, Denmark Hill, London, United Kingdom

  • Motohiko Oshima,

    Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Satoru Miyagi,

    Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Atsunori Saraya,

    Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Shuhei Koide,

    Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Tenyu Motoyama,

    Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Sadahisa Ogasawara,

    Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Yoshihiko Ooka,

    Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Akinobu Tawada,

    Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Tetsuya Nakatsura,

    Affiliation Division of Cancer Immunotherapy, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan

  • Takehiro Hayashi,

    Affiliation Department of Gastroenterology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan

  • Taro Yamashita,

    Affiliation Department of Gastroenterology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan

  • Syuichi Kaneko,

    Affiliation Department of Gastroenterology, Graduate School of Medicine, Kanazawa University, Kanazawa, Japan

  • Masaru Miyazaki,

    Affiliation Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan

  • Atsushi Iwama,

    Affiliation Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

  •  [ ... ],
  • Osamu Yokosuka

    Affiliation Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan

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