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Research Article

Insights from Zebrafish and Mouse Models on the Activity and Safety of Ar-Turmerone as a Potential Drug Candidate for the Treatment of Epilepsy

  • Adriana Monserrath Orellana-Paucar,

    Affiliations: Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium, Facultad de Ciencias Químicas, Escuela de Bioquímica y Farmacia, Universidad de Cuenca, Cuenca, Ecuador

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  • Tatiana Afrikanova,

    Affiliation: Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium

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  • Joice Thomas,

    Affiliation: Laboratory for Molecular Design and Synthesis, Department of Chemistry, University of Leuven, Leuven, Belgium

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  • Yelaman K. Aibuldinov,

    Affiliation: Laboratory for Molecular Design and Synthesis, Department of Chemistry, University of Leuven, Leuven, Belgium

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  • Wim Dehaen,

    Affiliation: Laboratory for Molecular Design and Synthesis, Department of Chemistry, University of Leuven, Leuven, Belgium

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  • Peter A. M. de Witte,

    Affiliation: Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium

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  • Camila V. Esguerra mail

    camila.esguerra@pharm.kuleuven.be

    Affiliation: Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium

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  • Published: December 13, 2013
  • DOI: 10.1371/journal.pone.0081634

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