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Open Access

Peer-reviewed

Research Article

Cannabinoid CB2 Receptors Regulate Central Sensitization and Pain Responses Associated with Osteoarthritis of the Knee Joint

  • James J. Burston ,

    Contributed equally to this work with: James J. Burston, Devi Rani Sagar

    Affiliations Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

    ⨯
  • Devi Rani Sagar ,

    Contributed equally to this work with: James J. Burston, Devi Rani Sagar

    Affiliations Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

    ⨯
  • Pin Shao,

    Affiliation Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Mingfeng Bai,

    Affiliations Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America

    ⨯
  • Emma King,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

    ⨯
  • Louis Brailsford,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

    ⨯
  • Jenna M. Turner,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

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  • Gareth J. Hathway,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

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  • Andrew J. Bennett,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

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  • David A. Walsh,

    Affiliation Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom

    ⨯
  • David A. Kendall,

    Affiliation School of Life Sciences, University of Nottingham, Nottingham, United Kingdom

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  • Aron Lichtman,

    Affiliation Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, United States of America

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  • Victoria Chapman

    victoria.chapman@nottingham.ac.uk

    Affiliation Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom

    ⨯

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