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Research Article

Latrunculin A Treatment Prevents Abnormal Chromosome Segregation for Successful Development of Cloned Embryos

  • Yukari Terashita mail,

    yterashita@cdb.riken.jp(YT); twakayama@yamanashi.ac.jp (TW)

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Laboratory of Animal Reproduction, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan

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  • Kazuo Yamagata,

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Center for genetic analysis of biological responses, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

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  • Mikiko Tokoro,

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Asada Institute for Reproductive Medicine, Asada Ladies Clinic, Kasugai, Japan

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  • Fumiaki Itoi,

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Asada Institute for Reproductive Medicine, Asada Ladies Clinic, Kasugai, Japan

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  • Sayaka Wakayama,

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Department of Biotechnology, Faculty of Life and Environmental Science, University of Yamanashi, Kofu, Japan

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  • Chong Li,

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, School of Medicine, Tongji University, Shanghai, China

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  • Eimei Sato,

    Affiliations: Laboratory of Animal Reproduction, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan, Managing director, National Livestock Breeding Center, Nishishirakawa-gun, Japan

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  • Kentaro Tanemura,

    Affiliation: Laboratory of Animal Reproduction, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan

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  • Teruhiko Wakayama mail

    yterashita@cdb.riken.jp(YT); twakayama@yamanashi.ac.jp (TW)

    Affiliations: Laboratory for Genomic Reprogramming, Center for Developmental Biology, RIKEN, Kobe, Japan, Department of Biotechnology, Faculty of Life and Environmental Science, University of Yamanashi, Kofu, Japan

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  • Published: October 24, 2013
  • DOI: 10.1371/journal.pone.0078380

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