Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB₂ Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis

• Sofia Sisay ,

  Contributed equally to this work with: Sofia Sisay, Gareth Pryce

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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• Gareth Pryce ,

  Contributed equally to this work with: Sofia Sisay, Gareth Pryce

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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• Samuel J. Jackson,

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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• Carolyn Tanner,

  Affiliation School of Medical Science, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom

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• Ruth A. Ross,

  Affiliations School of Medical Science, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom, Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada

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• Gregory J. Michael,

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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• David L. Selwood,

  Affiliation Biological and Medical Chemistry, the Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

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• Gavin Giovannoni,

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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• David Baker

  * E-mail: david.baker@qmul.ac.uk

  Affiliation Neuroimmunology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

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