Pax6 Is Required for Normal Cell-Cycle Exit and the Differentiation Kinetics of Retinal Progenitor Cells

Chen Farhy; Michael Elgart; Zehavit Shapira; Varda Oron-Karni; Orly Yaron; Yotam Menuchin; Gideon Rechavi; Ruth Ashery-Padan

doi:10.1371/journal.pone.0076489

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Peer-reviewed

Research Article

Pax6 Is Required for Normal Cell-Cycle Exit and the Differentiation Kinetics of Retinal Progenitor Cells

Chen Farhy,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Michael Elgart,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Zehavit Shapira,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Varda Oron-Karni,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Orly Yaron,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Yotam Menuchin,

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯
Gideon Rechavi,

Affiliation Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Ruth Ashery-Padan

* E-mail: ruthash@post.tau.ac.il

Affiliation Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯

Pax6 Is Required for Normal Cell-Cycle Exit and the Differentiation Kinetics of Retinal Progenitor Cells

Chen Farhy,
Michael Elgart,
Zehavit Shapira,
Varda Oron-Karni,
Orly Yaron,
Yotam Menuchin,
Gideon Rechavi,
Ruth Ashery-Padan

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Published: September 20, 2013
https://doi.org/10.1371/journal.pone.0076489

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Retina
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Cell differentiation
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Neuronal differentiation
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Gene expression
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Hedgehog signaling
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Cell cycle and cell division
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Precursor cells
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