High-Throughput Screening (HTS) and Hit Validation to Identify Small Molecule Inhibitors with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes

• Hyun Lee,

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Tian Zhu,

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Kavankumar Patel,

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Yan-Yan Zhang,

  Affiliation Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Lena Truong,

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Kirk E. Hevener,

  Current address: Department of Biomedical and Pharmaceutical Sciences, Idaho State University, Meridian, Idaho, United States of America

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Joseph L. Gatuz,

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Gitanjali Subramanya,

  Current address: Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America

  Affiliation Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Hyun-Young Jeong,

  Affiliation Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Susan L. Uprichard,

  Current address: Department of Medicine, Loyola University Medical Center, Maywood, Illinois, United States of America

  Affiliation Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯
• Michael E. Johnson

  * E-mail: mjohnson@uic.edu

  Affiliation Center for Pharmaceutical Biotechnology and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States of America

  ⨯