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Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model

  • Christine Tkaczyk,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Melissa M. Hamilton,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Vivekananda Datta,

    Affiliation Pathology Department, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Xiang Ping Yang,

    Affiliation Department of Respiratory, Inflammatory and Autoimmune Diseases, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Jamese J. Hilliard,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Geoffrey L. Stephens,

    Affiliation Department of Respiratory, Inflammatory and Autoimmune Diseases, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Agnieszka Sadowska,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Lei Hua,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Terrence O’Day,

    Affiliation Biostatistics Department, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • JoAnn Suzich,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Charles Kendall Stover,

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

  • Bret R. Sellman

    sellmanb@medimmune.com

    Affiliation Department of Infectious Disease, MedImmune, LLC, Gaithersburg, Maryland, United States of America

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