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Open Access

Peer-reviewed

Research Article

Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts

  • Gilles M. Leclerc,

    Affiliation Department of Pediatrics Hematology and Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Guy J. Leclerc,

    Affiliation Department of Pediatrics Hematology and Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Jeffim N. Kuznetsov,

    Affiliation Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Joanna DeSalvo,

    Affiliation Department of Pediatrics Hematology and Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Julio C. Barredo

    jbarredo@med.miami.edu

    Affiliations Department of Pediatrics Hematology and Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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