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Open Access

Peer-reviewed

Research Article

A Strategy to Model Nonmonotonic Dose-Response Curve and Estimate IC50

  • Hui Zhang ,

    hui.zhang@stjude.org

    Affiliation Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • Jeanne Holden-Wiltse,

    Affiliation Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Jiong Wang,

    Affiliation Department of Medicine and Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

    ⨯
  • Hua Liang

    Affiliation Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, United States of America

    ⨯

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