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Targeting the Giant Cell Tumor Stromal Cell: Functional Characterization and a Novel Therapeutic Strategy

  • Matthew R. Steensma ,

    matt.steensma@vai.org

    Affiliations Department of Surgery, Spectrum Health Medical Group/Michigan State University College of Human Medicine, Grand Rapids, Michigan, United States of America, Center for Skeletal Disease and Tumor Metastasis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

  • Wakenda K. Tyler,

    Affiliation Department of Orthopaedics, School of Medicine and Dentistry, University of Rochester, Rochester, New York, United States of America

  • Allison G. Shaber,

    Affiliation Research Division, Hospital for Special Surgery, New York, New York, United States of America

  • Steven R. Goldring,

    Affiliation Research Division, Hospital for Special Surgery, New York, New York, United States of America

  • F. Patrick Ross,

    Affiliation Research Division, Hospital for Special Surgery, New York, New York, United States of America

  • Bart O. Williams,

    Affiliation Center for Skeletal Disease and Tumor Metastasis, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

  • John H. Healey,

    Affiliation Orthopaedic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

  • P. Edward Purdue

    Affiliation Research Division, Hospital for Special Surgery, New York, New York, United States of America

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