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Asparagine Substitution at PB2 Residue 701 Enhances the Replication, Pathogenicity, and Transmission of the 2009 Pandemic H1N1 Influenza A Virus

  • Bin Zhou,

    Affiliations J. Craig Venter Institute, Rockville, Maryland, United States of America, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, New York, United States of America

  • Melissa B. Pearce,

    Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • Yan Li,

    Affiliation Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

  • Jieru Wang,

    Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

  • Robert J. Mason,

    Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

  • Terrence M. Tumpey,

    Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • David E. Wentworth

    dwentworth@JCVI.org

    Affiliations J. Craig Venter Institute, Rockville, Maryland, United States of America, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, New York, United States of America

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