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BAK and NOXA Are Critical Determinants of Mitochondrial Apoptosis Induced by Bortezomib in Mesothelioma

  • Sara Busacca,

    Affiliation Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom

  • Alex D. Chacko,

    Affiliation Centre for Cancer Research and Cell Biology, Queen’s University of Belfast, Belfast, Northern Ireland

  • Astero Klabatsa,

    Affiliation Division of Cancer Studies, Department of Research Oncology, King’s College London, London, United Kingdom

  • Kenneth Arthur,

    Affiliation Centre for Cancer Research and Cell Biology, Queen’s University of Belfast, Belfast, Northern Ireland

  • Michael Sheaff,

    Affiliation Department of Cellular Pathology, Barts and the London NHS Trust, London, United Kingdom

  • Vignesh K. Gunasekharan,

    Affiliation Department of Microbiology-Immunology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  • Julia J. Gorski,

    Affiliation Centre for Cancer Research and Cell Biology, Queen’s University of Belfast, Belfast, Northern Ireland

  • Mohamed El-Tanani,

    Affiliation Centre for Cancer Research and Cell Biology, Queen’s University of Belfast, Belfast, Northern Ireland

  • V. Courtney Broaddus,

    Affiliation Lung Biology Centre, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

  • Giovanni Gaudino,

    Affiliation University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America

  • Dean A. Fennell

    df132@le.ac.uk

    Affiliation Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, United Kingdom

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