Genome-Wide Small RNA Sequencing and Gene Expression Analysis Reveals a microRNA Profile of Cancer Susceptibility in ATM-Deficient Human Mammary Epithelial Cells

Jill E. Hesse; Liwen Liu; Cynthia L. Innes; Yuxia Cui; Stela S. Palii; Richard S. Paules

doi:10.1371/journal.pone.0064779

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Research Article

Genome-Wide Small RNA Sequencing and Gene Expression Analysis Reveals a microRNA Profile of Cancer Susceptibility in ATM-Deficient Human Mammary Epithelial Cells

Jill E. Hesse,

Affiliation Environmental Stress and Cancer Group, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
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Liwen Liu,

Affiliation NIEHS Microarray Core, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
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Cynthia L. Innes,

Affiliation Environmental Stress and Cancer Group, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
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Yuxia Cui,

Affiliation Environmental Stress and Cancer Group, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
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Stela S. Palii,

Affiliation Environmental Stress and Cancer Group, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
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Richard S. Paules

* E-mail: paules@niehs.nih.gov

Affiliations Environmental Stress and Cancer Group, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America, NIEHS Microarray Core, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
⨯

Genome-Wide Small RNA Sequencing and Gene Expression Analysis Reveals a microRNA Profile of Cancer Susceptibility in ATM-Deficient Human Mammary Epithelial Cells

Jill E. Hesse,
Liwen Liu,
Cynthia L. Innes,
Yuxia Cui,
Stela S. Palii,
Richard S. Paules

x

Published: May 31, 2013
https://doi.org/10.1371/journal.pone.0064779

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MicroRNAs
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Breast cancer
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Gene expression
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RNA sequencing
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Gene regulation
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Epithelial cells
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Human genomics
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Messenger RNA
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