A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies

• Song Xuejiao ,

  Contributed equally to this work with: Song Xuejiao, Xia Yong

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Xia Yong ,

  Contributed equally to this work with: Song Xuejiao, Xia Yong

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Wang Ningyu,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Zhang Lidan,

  Affiliation Department of Pharmaceutical and Bioengineering, School of Chemical Engineering, Sichuan University, Chengdu, China

  ⨯
• Shi Xuanhong,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Xu Youzhi,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Ye Tinghong,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Shi Yaojie,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Zhu Yongxia,

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯
• Yu Luoting

  * E-mail: yuluot@scu.edu.cn

  Affiliation State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, China

  ⨯