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Research Article

In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors

  • Mahiuddin Ahmed,

    Affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Yehuda Goldgur,

    Affiliation: Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Jian Hu,

    Affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Hong-Fen Guo,

    Affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Nai-Kong V. Cheung mail

    cheungn@mskcc.org

    Affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Published: May 16, 2013
  • DOI: 10.1371/journal.pone.0063359

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