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Research Article

Tumor Derived Mutations of Protein Tyrosine Phosphatase Receptor Type K Affect Its Function and Alter Sensitivity to Chemotherapeutics in Glioma

  • Supreet Agarwal,

    Affiliation: Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, United States of America

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  • Maha S. Al-Keilani,

    Affiliation: Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, United States of America

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  • Mohammad A. Y. Alqudah,

    Affiliation: Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, United States of America

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  • Zita A. Sibenaller,

    Affiliation: Department of Neurosurgery and Radiation Oncology, University of Iowa, Iowa City, Iowa, United States of America

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  • Timothy C. Ryken,

    Affiliations: Department of Neurosurgery and Radiation Oncology, University of Iowa, Iowa City, Iowa, United States of America, Department of Neurosurgery, Iowa Spine and Brain Institute, Waterloo, Iowa, United States of America

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  • Mahfoud Assem mail

    mahfoud-assem@uiowa.edu

    Affiliation: Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, United States of America

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  • Published: May 16, 2013
  • DOI: 10.1371/journal.pone.0062852

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