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Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease

  • Amanda L. Wright,

    Affiliations Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

  • Raphael Zinn,

    Affiliations Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

  • Barbara Hohensinn,

    Current address: Institute of Molecular Biosciences, University of Graz, Graz, Austria

    Affiliations Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

  • Lyndsey M. Konen,

    Affiliation Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia

  • Sarah B. Beynon,

    Current address: School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia

    Affiliation Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia

  • Richard P. Tan,

    Affiliation Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia

  • Ian A. Clark,

    Affiliation Research School of Biology, Australian National University, Canberra, Australia

  • Andrea Abdipranoto,

    Affiliation Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia

  • Bryce Vissel

    b.vissel@garvan.org.au

    Affiliations Neurodegenerative Disorders, Garvan Institute of Medical Research, Neuroscience Department, Sydney, Australia, Faculty of Medicine, University of New South Wales, Sydney, Australia

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