Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα

• Mohamed E. Moustafa ,

  Contributed equally to this work with: Mohamed E. Moustafa, Bradley A. Carlson, Miriam R. Anver, Gerd Bobe

  Current address: Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria, Egypt

  Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Bradley A. Carlson ,

  Contributed equally to this work with: Mohamed E. Moustafa, Bradley A. Carlson, Miriam R. Anver, Gerd Bobe

  Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Miriam R. Anver ,

  Contributed equally to this work with: Mohamed E. Moustafa, Bradley A. Carlson, Miriam R. Anver, Gerd Bobe

  Affiliation Pathology/Histotechnology Laboratory, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Gerd Bobe ,

  Contributed equally to this work with: Mohamed E. Moustafa, Bradley A. Carlson, Miriam R. Anver, Gerd Bobe

  Affiliation Department of Animal and Rangeland Sciences, College of Agriculture, and Linus Pauling Institute, Oregon State University, Corvallis, Oregon, United States of America

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• Nianxin Zhong,

  Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Jerrold M. Ward,

  Affiliation Immunopathology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Christine M. Perella,

  Affiliation Laboratory Animal Sciences Program, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Victoria J. Hoffmann,

  Affiliation Office of the Director, Diagnostic and Research Services Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Keith Rogers,

  Current address: Histopathology Laboratory, Institute of Molecular and Cell Biology, Proteos, Singapore

  Affiliation Pathology/Histotechnology Laboratory, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Gerald F. Combs Jr,

  Affiliation Grand Forks Human Nutrition Research Center, Grand Forks, North Dakota, United States of America

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• Ulrich Schweizer,

  Affiliation Charite-Universitatsmedizin Berlin, Institut fur Experimentelle Endokrinologie, Berlin, Germany

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• Glenn Merlino,

  Affiliation Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Vadim N. Gladyshev,

  Affiliation Division of Genetics, Department of Medicine, Brigham & Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Dolph L. Hatfield

  * E-mail: hatfield@dc37a.nci.nih.gov

  Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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