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Research Article

Conditional Knockout of Integrin α2β1 in Murine Megakaryocytes Leads to Reduced Mean Platelet Volume

  • David Habart,

    Affiliation: Roon Research Center for Arteriosclerosis and Thrombosis, The Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America

    Current address: Islet Transplant Laboratory, Diabetes Centre, Institute of Clinical and Experimental Medicine, Prague, Czech Republic

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  • Yann Cheli,

    Affiliation: Roon Research Center for Arteriosclerosis and Thrombosis, The Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America

    Current address: INSERM, U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), Equipe 1, Biology and Pathologies of Melanocytes, Nice, France

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  • Diane J. Nugent,

    Affiliation: Hematology Research, CHOC Children's Hospital, Orange, California, United States of America

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  • Zaverio M. Ruggeri,

    Affiliation: Roon Research Center for Arteriosclerosis and Thrombosis, The Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America

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  • Thomas J. Kunicki mail

    tkunicki@choc.org

    Affiliations: Roon Research Center for Arteriosclerosis and Thrombosis, The Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America, Hematology Research, CHOC Children's Hospital, Orange, California, United States of America

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  • Published: January 24, 2013
  • DOI: 10.1371/journal.pone.0055094

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