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Open Access

Peer-reviewed

Research Article

Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease

  • Ping He,

    Affiliation Center for Advanced Therapeutic Strategies of Brain Disorders, Roskamp Institute, Sarasota, Florida, United States of America

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  • Xin Cheng,

    Affiliation Department of Neurology and Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China

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  • Matthias Staufenbiel,

    Affiliation Novartis Pharm Ltd., Nervous System Research, Basel, Switzerland

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  • Rena Li,

    Affiliation Center for Hormone Advanced Science and Education, Roskamp Institute, Sarasota, Florida, United States of America

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  • Yong Shen

    yshen@rfdn.org

    Affiliations Center for Advanced Therapeutic Strategies of Brain Disorders, Roskamp Institute, Sarasota, Florida, United States of America, Department of Neurology and Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China

    ⨯

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