Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay

• Kazunori Sano,

  Affiliations Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Global Centers of Excellence Program, Nagasaki University, Nagasaki, Japan

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• Katsuya Satoh ,

  * E-mail: satoh-prion@nagasaki-u.ac.jp

  Affiliation Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

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• Ryuichiro Atarashi,

  Affiliations Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Nagasaki University Research Centre for Genomic Instability and Carcinogenesis, Nagasaki University, Nagasaki, Japan

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• Hiroshi Takashima,

  Affiliation Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

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• Yasushi Iwasaki,

  Affiliation Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Aichi, Japan

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• Mari Yoshida,

  Affiliation Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Aichi, Japan

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• Nobuo Sanjo,

  Affiliation Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan

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• Hiroyuki Murai,

  Affiliation Department of Neurology, Iizuka Hospital, Fukuoka, Japan

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• Hidehiro Mizusawa,

  Affiliation Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan

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• Matthias Schmitz,

  Affiliation Dementia Research Unit, National Reference Center for TSE, Georg-August University, Göttingen, Germany

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• Inga Zerr,

  Affiliation Dementia Research Unit, National Reference Center for TSE, Georg-August University, Göttingen, Germany

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• Yong-Sun Kim,

  Affiliation Ilsong Institute of Life Science, Hallym University, Gyeonggi-Do, Republic of Korea

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• Noriyuki Nishida

  Affiliations Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, Global Centers of Excellence Program, Nagasaki University, Nagasaki, Japan

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