Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

• Richard A. Jensen ,

  * E-mail: richaj@uw.edu

  ¶# First author from each of the cohorts involved in the study.

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America

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• Xueling Sim ,

  ¶# First author from each of the cohorts involved in the study.

  Affiliation Centre for Molecular Epidemiology, National University of Singapore, Singapore, Singapore

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• Xiaohui Li ,

  ¶# First author from each of the cohorts involved in the study.

  Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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• Mary Frances Cotch ,

  ¶# First author from each of the cohorts involved in the study.

  Affiliation Division of Epidemiology and Clinical Applications, National Eye Institute, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, United States of America

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• M. Kamran Ikram ,

  ¶# First author from each of the cohorts involved in the study.

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Elizabeth G. Holliday ,

  ¶# First author from each of the cohorts involved in the study.

  Affiliation School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia

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• Gudny Eiriksdottir,

  Affiliation Icelandic Heart Association, Kopavogur, Iceland

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• Tamara B. Harris,

  Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, United States of America

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• Fridbert Jonasson,

  Affiliations Department of Medicine, University of Iceland, Reykjavik, Iceland, Department of Ophthalmology, Landspitalinn University Hospital, Reykjavik, Iceland

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• Barbara E. K. Klein,

  Affiliation Department of Ophthalmology and Visual Science, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America

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• Lenore J. Launer,

  Affiliation Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, United States of America

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• Albert Vernon Smith,

  Affiliations Icelandic Heart Association, Kopavogur, Iceland, Department of Medicine, University of Iceland, Reykjavik, Iceland

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• Eric Boerwinkle,

  Affiliation Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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• Ning Cheung,

  Affiliation Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia

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• Alex W. Hewitt,

  Affiliation Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia

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• Gerald Liew,

  Affiliations Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia, Centre for Vision Research, Department of Ophthalmology and the Westmead Millennium Institute, University of Sydney, Sydney, Australia

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• Paul Mitchell,

  Affiliation Centre for Vision Research, Department of Ophthalmology and the Westmead Millennium Institute, University of Sydney, Sydney, Australia

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• Jie Jin Wang,

  Affiliations Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia, Centre for Vision Research, Department of Ophthalmology and the Westmead Millennium Institute, University of Sydney, Sydney, Australia

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• John Attia,

  Affiliations School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia, Department of Medicine, John Hunter Hospital and Hunter Medical Research Institute, Newcastle, New South Wales, Australia

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• Rodney Scott,

  Affiliation School of Biomedical Sciences, University of Newcastle, Newcastle, New South Wales, Australia

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• Nicole L. Glazer,

  Affiliation Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• Thomas Lumley,

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Statistics, University of Auckland, Auckland, New Zealand

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• Barbara McKnight,

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

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• Bruce M. Psaty,

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America, Department of Health Services, University of Washington, Seattle, Washington, United States of America, Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America

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• Kent Taylor,

  Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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• Albert Hofman,

  Affiliation Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Paulus T. V. M. de Jong,

  Affiliations Netherlands Institute of Neuroscience, Amsterdam, The Netherlands, Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands

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• Fernando Rivadeneira,

  Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

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• Andre G. Uitterlinden,

  Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, The Netherlands

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• Wan-Ting Tay,

  Affiliation Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

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• Yik Ying Teo,

  Affiliations Centre for Molecular Epidemiology, National University of Singapore, Singapore, Singapore, Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore, Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore, NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore, Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore

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• Mark Seielstad,

  Affiliation Institute of Human Genetics, University of California San Francisco, San Francisco, California United States of America

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• Jianjun Liu,

  Affiliation Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore

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• Ching-Yu Cheng,

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore, Department of Ophthalmology, National University of Singapore, Singapore, Singapore

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• Seang-Mei Saw,

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore, Department of Ophthalmology, National University of Singapore, Singapore, Singapore

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• Tin Aung,

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Department of Ophthalmology, National University of Singapore, Singapore, Singapore

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• Santhi K. Ganesh,

  Affiliation Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Christopher J. O'Donnell,

  Affiliations National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, United States of America, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Mike A. Nalls,

  Affiliation Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

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• Kerri L. Wiggins,

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America

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• Jane Z. Kuo,

  Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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• The Blue Mountains Eye Study GWAS team ,

  ¶‡ Membership is provided in the acknowledgements.

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• CKDGen Consortium ,

  ¶‡ Membership is provided in the acknowledgements.

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• Cornelia M. van Duijn ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliation Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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• Vilmundur Gudnason ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliations Icelandic Heart Association, Kopavogur, Iceland, Department of Medicine, University of Iceland, Reykjavik, Iceland

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• Ronald Klein ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliation Department of Ophthalmology and Visual Science, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America

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• David S. Siscovick ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliations Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

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• Jerome I. Rotter ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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• E. Shong Tai ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliations Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore, Department of Medicine, National University of Singapore, Singapore, Singapore, Duke-National University of Singapore Graduate Medical School, Singapore, Singapore

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• Johannes Vingerling ,

  ¶Senior author from each of the cohorts involved in the study.

  Affiliations Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

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•  [ ... ],
• Tien Y. Wong

  ¶Senior author from each of the cohorts involved in the study.

  Affiliations Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore, Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia, Department of Ophthalmology, National University of Singapore, Singapore, Singapore

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