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Research Article

Selective Protection of Human Liver Tissue in TNF-Targeting of Cancers of the Liver by Transient Depletion of Adenosine Triphosphate

  • Timo Weiland,

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Kathrin Klein,

    Affiliation: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany

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  • Martina Zimmermann,

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Tobias Speicher,

    Affiliation: Department of Biology, Institute of Cell Biology, ETH Zürich, Switzerland

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  • Sascha Venturelli,

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Alexander Berger,

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Heike Bantel,

    Affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Alfred Königsrainer,

    Affiliation: Department of General, Visceral & Transplant Surgery, University Hospital, Tuebingen, Germany

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  • Martin Schenk,

    Affiliation: Department of General, Visceral & Transplant Surgery, University Hospital, Tuebingen, Germany

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  • Thomas S. Weiss,

    Affiliation: Center for Liver Cell Research, University Hospital, Regensburg, Germany

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  • Albrecht Wendel,

    Affiliation: Interfaculty Center for Pharmacogenomics and Drug Research (ICEPHA), University of Tuebingen, Germany

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  • Matthias Schwab,

    Affiliations: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany, Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, Medical University Hospital, Tuebingen, Germany

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  • Michael Bitzer,

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Ulrich M. Lauer mail

    ulrich.lauer@uni-tuebingen.de

    Affiliation: Department of Internal Medicine I, Medical University Hospital, Tuebingen, Germany

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  • Published: December 18, 2012
  • DOI: 10.1371/journal.pone.0052496

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