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Residual Expression of Reprogramming Factors Affects the Transcriptional Program and Epigenetic Signatures of Induced Pluripotent Stem Cells

  • Cesar A. Sommer ,

    Contributed equally to this work with: Cesar A. Sommer, Constantina Christodoulou, Andreia Gianotti-Sommer

    Affiliation Section of Gastroenterology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Constantina Christodoulou ,

    Contributed equally to this work with: Cesar A. Sommer, Constantina Christodoulou, Andreia Gianotti-Sommer

    Affiliation Boston University Pulmonary Center, and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Andreia Gianotti-Sommer ,

    Contributed equally to this work with: Cesar A. Sommer, Constantina Christodoulou, Andreia Gianotti-Sommer

    Affiliation Section of Gastroenterology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Steven S. Shen,

    Affiliation Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Badi Sri Sailaja,

    Affiliation Department of Genetics, Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel

  • Hadas Hezroni,

    Affiliation Department of Genetics, Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel

  • Avrum Spira,

    Affiliation Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Eran Meshorer,

    Affiliation Department of Genetics, Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel

  • Darrell N. Kotton ,

    gmostosl@bu.edu (GM); dkotton@bu.edu (DNK)

    Affiliations Boston University Pulmonary Center, and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, Massachusetts, United States of America

  • Gustavo Mostoslavsky

    gmostosl@bu.edu (GM); dkotton@bu.edu (DNK)

    Affiliations Section of Gastroenterology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, Massachusetts, United States of America

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