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Research Article

Ex Vivo Evidence for the Contribution of Hemodynamic Shear Stress Abnormalities to the Early Pathogenesis of Calcific Bicuspid Aortic Valve Disease

  • Ling Sun,

    Affiliations: Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

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  • Santanu Chandra,

    Affiliation: Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America

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  • Philippe Sucosky mail

    Philippe.Sucosky@nd.edu

    Affiliations: Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America, Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

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  • Published: October 31, 2012
  • DOI: 10.1371/journal.pone.0048843

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