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Open Access

Peer-reviewed

Research Article

Chronic Temporal Lobe Epilepsy Is Associated with Enhanced Alzheimer-Like Neuropathology in 3×Tg-AD Mice

  • Xiao-Xin Yan ,

    yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

    Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

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  • Yan Cai,

    Affiliations Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China, Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

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  • Jarod Shelton,

    Affiliation Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

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  • Si-Hao Deng,

    Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

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  • Xue-Gang Luo,

    Affiliation Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha, Hunan, China

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  • Salvatore Oddo,

    Affiliation Department of Physiology and The Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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  • Frank M. LaFerla,

    Affiliation Department of Neurobiology and Behavior, University of California Irvine, Irvine, California, United States of America

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  • Huaibin Cai,

    Affiliation Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America

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  • Gregory M. Rose ,

    yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

    Affiliations Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

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  • Peter R. Patrylo

    yanxiaoxin@csu.edu.cn (XXY); grose@siumed.edu (GMR); ppatrylo@siu.edu (PRP)

    Affiliations Center for Integrated Research in Cognitive and Neural Sciences, Southern Illinois University Carbondale, Illinois, United States of America, Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois, United States of America

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