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Research Article

Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery

  • Peter S. Kutchukian,

    Affiliation: Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America

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  • Nadya Y. Vasilyeva,

    Affiliation: Department of Psychology, Northeastern University, Boston, Massachusetts, United States of America

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  • Jordan Xu,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

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  • Mika K. Lindvall,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

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  • Michael P. Dillon,

    Affiliation: Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, California, United States of America

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  • Meir Glick,

    Affiliation: Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America

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  • John D. Coley mail,

    j.coley@neu.edu (JDC); NBrooijmans@blueprintmedicines.com (NB)

    Affiliation: Department of Psychology, Northeastern University, Boston, Massachusetts, United States of America

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  • Natasja Brooijmans mail

    j.coley@neu.edu (JDC); NBrooijmans@blueprintmedicines.com (NB)

    Affiliation: Blueprint Medicines, Cambridge, Massachusetts, United States of America

    X
  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0048476

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