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Open Access

Peer-reviewed

Research Article

FREQ-Seq: A Rapid, Cost-Effective, Sequencing-Based Method to Determine Allele Frequencies Directly from Mixed Populations

  • Lon M. Chubiz ,

    Contributed equally to this work with: Lon M. Chubiz, Ming-Chun Lee

    Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Ming-Chun Lee ,

    Contributed equally to this work with: Lon M. Chubiz, Ming-Chun Lee

    Current address: Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong

    Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

    ⨯
  • Nigel F. Delaney,

    Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

    ⨯
  • Christopher J. Marx

    cmarx@oeb.harvard.edu

    Affiliations Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America, Faculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

    ⨯

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