Spermine Attenuates the Action of the DNA Intercalator, Actinomycin D, on DNA Binding and the Inhibition of Transcription and DNA Replication

• Sheng-Yu Wang ,

  Contributed equally to this work with: Sheng-Yu Wang, Yueh-Luen Lee, Yi-Hua Lai

  Affiliations Department of Life Science, National Chung Hsing University, Taichung, Taiwan, Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan

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• Yueh-Luen Lee ,

  Contributed equally to this work with: Sheng-Yu Wang, Yueh-Luen Lee, Yi-Hua Lai

  Affiliation National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan

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• Yi-Hua Lai ,

  Contributed equally to this work with: Sheng-Yu Wang, Yueh-Luen Lee, Yi-Hua Lai

  Affiliation Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan

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• Jeremy J. W. Chen,

  Affiliation Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan

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• Wen-Lin Wu,

  Affiliation Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan

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• Jeu-Ming P. Yuann,

  Affiliation Department of Biotechnology, Ming Chuan University, Taoyuan County, Taiwan

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• Wang-Lin Su,

  Affiliation Department of Life Science, National Chung Hsing University, Taichung, Taiwan

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• Show-Mei Chuang,

  Affiliation Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan

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• Ming-Hon Hou

  * E-mail: mhho@dragon.nchu.edu.tw

  Affiliations Department of Life Science, National Chung Hsing University, Taichung, Taiwan, Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan

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