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Research Article

Regulation of the CCL2 Gene in Pancreatic β-Cells by IL-1β and Glucocorticoids: Role of MKP-1

  • Susan J. Burke,

    Affiliation: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Matthew R. Goff,

    Affiliation: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Barrett L. Updegraff,

    Affiliation: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Danhong Lu,

    Affiliation: Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Patricia L. Brown,

    Affiliation: Advanced Microscopy and Imaging Center, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Steven C. Minkin Jr.,

    Affiliation: Advanced Microscopy and Imaging Center, University of Tennessee, Knoxville, Tennessee, United States of America

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  • John P. Biggerstaff,

    Affiliation: Advanced Microscopy and Imaging Center, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Ling Zhao,

    Affiliations: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America, University of Tennessee Obesity Research Center, Knoxville, Tennessee, United States of America

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  • Michael D. Karlstad,

    Affiliations: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America, Department of Surgery, Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, Tennessee, United States of America, University of Tennessee Obesity Research Center, Knoxville, Tennessee, United States of America

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  • J. Jason Collier mail

    Jason.Collier@utk.edu

    Affiliations: Department of Nutrition, University of Tennessee, Knoxville, Tennessee, United States of America, University of Tennessee Obesity Research Center, Knoxville, Tennessee, United States of America

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0046986

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