Pax6 Directly Down-Regulates Pcsk1n Expression Thereby Regulating PC1/3 Dependent Proinsulin Processing

Ting Liu; Yanxia Zhao; Na Tang; Ruopeng Feng; Xiaolong Yang; Nicole Lu; Jinhua Wen; Lingsong Li

doi:10.1371/journal.pone.0046934

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Peer-reviewed

Research Article

Pax6 Directly Down-Regulates Pcsk1n Expression Thereby Regulating PC1/3 Dependent Proinsulin Processing

Ting Liu,

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Yanxia Zhao,

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Na Tang,

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Ruopeng Feng,

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Xiaolong Yang,

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Nicole Lu,

Affiliation SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, CAS, Shanghai, China
⨯
Jinhua Wen ,

* E-mail: jhwen@bjmu.edu.cn

Affiliation Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Lingsong Li

Affiliations Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, CAS, Shanghai, China
⨯

Pax6 Directly Down-Regulates Pcsk1n Expression Thereby Regulating PC1/3 Dependent Proinsulin Processing

Ting Liu,
Yanxia Zhao,
Na Tang,
Ruopeng Feng,
Xiaolong Yang,
Nicole Lu,
Jinhua Wen,
Lingsong Li

x

Published: October 9, 2012
https://doi.org/10.1371/journal.pone.0046934

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