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Research Article

Pax6 Directly Down-Regulates Pcsk1n Expression Thereby Regulating PC1/3 Dependent Proinsulin Processing

  • Ting Liu,

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Yanxia Zhao,

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Na Tang,

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Ruopeng Feng,

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Xiaolong Yang,

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Nicole Lu,

    Affiliation: SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, CAS, Shanghai, China

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  • Jinhua Wen mail,

    jhwen@bjmu.edu.cn

    Affiliation: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China

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  • Lingsong Li

    Affiliations: Peking University Stem Cell Research Center, and Department of Cell Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, SARI Center for Stem Cell and Nanomedicine, Shanghai Advanced Research Institute, CAS, Shanghai, China

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0046934

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