Adipose Tissue Promotes a Serum Cytokine Profile Related to Lower Insulin Sensitivity after Chronic Central Leptin Infusion

Emma Burgos-Ramos; Sandra Canelles; Arancha Perianes-Cachero; Eduardo Arilla-Ferreiro; Jesús Argente; Vicente Barrios

doi:10.1371/journal.pone.0046893

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Research Article

Adipose Tissue Promotes a Serum Cytokine Profile Related to Lower Insulin Sensitivity after Chronic Central Leptin Infusion

Emma Burgos-Ramos,

Affiliations Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa and Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain, Centro de Investigación Biomédica en Red Fisiopatología de Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
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Sandra Canelles,

Affiliations Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa and Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain, Centro de Investigación Biomédica en Red Fisiopatología de Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
⨯
Arancha Perianes-Cachero,

Affiliation Grupo de Neurobioquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Alcalá, Alcalá de Henares, Spain
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Eduardo Arilla-Ferreiro,

Affiliation Grupo de Neurobioquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Alcalá, Alcalá de Henares, Spain
⨯
Jesús Argente,

Affiliations Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa and Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain, Centro de Investigación Biomédica en Red Fisiopatología de Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
⨯
Vicente Barrios

* E-mail: vbarrios@telefonica.net

Affiliations Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa and Department of Pediatrics, Universidad Autónoma de Madrid, Madrid, Spain, Centro de Investigación Biomédica en Red Fisiopatología de Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
⨯

Adipose Tissue Promotes a Serum Cytokine Profile Related to Lower Insulin Sensitivity after Chronic Central Leptin Infusion

Emma Burgos-Ramos,
Sandra Canelles,
Arancha Perianes-Cachero,
Eduardo Arilla-Ferreiro,
Jesús Argente,
Vicente Barrios

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Published: October 2, 2012
https://doi.org/10.1371/journal.pone.0046893

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Leptin
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Adipose tissue
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Insulin
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Cytokines
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Inflammation
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Insulin resistance
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Food
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Insulin signaling
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