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Open Access

Peer-reviewed

Research Article

Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness

  • Gabriel Navarro,

    Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Supchar Chokpaiboon,

    Affiliation Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

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  • Geraldine De Muylder,

    Affiliation Sandler Center for Basic Research in Parasitic Disease, University of California San Francisco, San Francisco, California, United States of America

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  • Walter M. Bray,

    Affiliation Chemical Screening Center, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Sean C. Nisam,

    Affiliation Chemical Screening Center, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • James H. McKerrow,

    Affiliation Sandler Center for Basic Research in Parasitic Disease, University of California San Francisco, San Francisco, California, United States of America

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  • Khanitha Pudhom,

    Affiliation Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

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  • Roger G. Linington

    rliningt@ucsc.edu

    Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California, United States of America

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