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Arhgef15 Promotes Retinal Angiogenesis by Mediating VEGF-Induced Cdc42 Activation and Potentiating RhoJ Inactivation in Endothelial Cells

  • Sentaro Kusuhara ,

    Contributed equally to this work with: Sentaro Kusuhara, Yoko Fukushima

    Affiliations Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan, Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

  • Yoko Fukushima ,

    Contributed equally to this work with: Sentaro Kusuhara, Yoko Fukushima

    Affiliations Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan, Division of Vascular Biology, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan, Department of Ophthalmology, Osaka University Medical School, Osaka, Japan

  • Shigetomo Fukuhara,

    Affiliation Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

  • Lars Martin Jakt,

    Affiliation Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan

  • Mitsuhiro Okada,

    Affiliation Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan

  • Yuri Shimizu,

    Affiliation Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan

  • Masayuki Hata,

    Affiliation Division of Vascular Biology, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan

  • Kohji Nishida,

    Affiliation Department of Ophthalmology, Osaka University Medical School, Osaka, Japan

  • Akira Negi,

    Affiliation Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

  • Masanori Hirashima,

    Affiliation Division of Vascular Biology, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan

  • Naoki Mochizuki,

    Affiliation Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

  • Shin-Ichi Nishikawa,

    Affiliation Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan

  • Akiyoshi Uemura

    auemura@med.kobe-u.ac.jp

    Affiliations Laboratory for Stem Cell Biology, RIKEN Center for Developmental Biology, Kobe, Japan, Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan, Division of Vascular Biology, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan

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