Structural Basis of Type 2A von Willebrand Disease Investigated by Molecular Dynamics Simulations and Experiments

Open Access

Peer-reviewed

Research Article

Gianluca Interlandi ,

* E-mail: gianluca@u.washington.edu

Affiliation Department of Bioengineering, University of Washington, Seattle, Washington, United States of America
⨯
Minhua Ling,

Affiliation Department of Biochemistry, University of Washington, Seattle, Washington, United States of America
⨯
An Yue Tu,

Affiliation Department of Bioengineering, University of Washington, Seattle, Washington, United States of America
⨯
Dominic W. Chung,

Affiliation Department of Biochemistry, University of Washington, Seattle, Washington, United States of America
⨯
Wendy E. Thomas

Affiliation Department of Bioengineering, University of Washington, Seattle, Washington, United States of America
⨯

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Biochemical simulations
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Urea
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Point mutation
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von Willebrand disease
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Protein structure
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Biotin
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Crystal structure
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Molecular dynamics
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