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Triterpenoid Dihydro-CDDO-Trifluoroethyl Amide Protects against Maladaptive Cardiac Remodeling and Dysfunction in Mice: A Critical Role of Nrf2

  • Yifan Xing,

    Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Traditional Medicine, Qilu Hospital of Shandong University, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Ting Niu,

    Affiliation Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China

  • Wenjuan Wang,

    Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Jinqing Li,

    Affiliation Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Siying Li,

    Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Joseph S. Janicki,

    Affiliation Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Stacey Ruiz,

    Affiliation Department of Pharmacology, Reata Pharmaceuticals, Inc., Irving, Texas, United States of America

  • Colin J. Meyer,

    Affiliation Department of Pharmacology, Reata Pharmaceuticals, Inc., Irving, Texas, United States of America

  • Xing Li Wang,

    Affiliation Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China

  • Dongqi Tang,

    Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

  • Yuxia Zhao ,

    yuxia_zhao@126.com (YZ); taixing.cui@uscmed.sc.edu (TC)

    Affiliation Department of Traditional Medicine, Qilu Hospital of Shandong University, Jinan, China

  • Taixing Cui

    yuxia_zhao@126.com (YZ); taixing.cui@uscmed.sc.edu (TC)

    Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

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