Caffeine-Induced Activated Glucocorticoid Metabolism in the Hippocampus Causes Hypothalamic-Pituitary-Adrenal Axis Inhibition in Fetal Rats

Open Access

Peer-reviewed

Research Article

Dan Xu,

Affiliations Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China, Research Center of Food and Drug Evaluation, Wuhan University, Wuhan, China
⨯
Benjian Zhang,

Affiliation Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China
⨯
Gai Liang,

Affiliation Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China
⨯
Jie Ping,

Affiliations Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China, Research Center of Food and Drug Evaluation, Wuhan University, Wuhan, China
⨯
Hao Kou,

Affiliation Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China
⨯
Xiaojun Li,

Affiliation Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China
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Jie Xiong,

Affiliation Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China
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Dongcai Hu,

Affiliation Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China
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Liaobin Chen,

Affiliation Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China
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Jacques Magdalou,

Affiliation UMR 7561 CNRS-Nancy Université, Faculté de Médicine, Vandoeuvre-lès-Nancy, France
⨯
Hui Wang

* E-mail: wanghui19@whu.edu.cn

Affiliations Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan, China, Research Center of Food and Drug Evaluation, Wuhan University, Wuhan, China
⨯

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Caffeine
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Hippocampus
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DNA methylation
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Ingestion
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Pregnancy
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Gene expression
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Protein expression
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Metabolic syndrome
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