Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach

Dean B. Everett; Jennifer Cornick; Brigitte Denis; Claire Chewapreecha; Nicholas Croucher; Simon Harris; Julian Parkhill; Stephen Gordon; Enitan D. Carrol; Neil French; Robert S. Heyderman; Stephen D. Bentley

doi:10.1371/journal.pone.0044250

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Open Access

Peer-reviewed

Research Article

Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach

Dean B. Everett ,

* E-mail: Dean.Everett@liverpool.ac.uk

Affiliations Malawi-Liverpool-Wellcome Clinical Research Programme, Chichiri, Blantyre 3, Malawi, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom
⨯
Jennifer Cornick,

Affiliations Malawi-Liverpool-Wellcome Clinical Research Programme, Chichiri, Blantyre 3, Malawi, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom
⨯
Brigitte Denis,

Affiliation Malawi-Liverpool-Wellcome Clinical Research Programme, Chichiri, Blantyre 3, Malawi
⨯
Claire Chewapreecha,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Nicholas Croucher,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Simon Harris,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Julian Parkhill,

Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯
Stephen Gordon,

Affiliation The Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Enitan D. Carrol,

Affiliation Department of Women’s and Children’s Health, Institute of Child Health, University of Liverpool, Liverpool, United Kingdom
⨯
Neil French,

Affiliation Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom
⨯
Robert S. Heyderman,

Affiliations Malawi-Liverpool-Wellcome Clinical Research Programme, Chichiri, Blantyre 3, Malawi, The Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Stephen D. Bentley

Affiliations Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
⨯

Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach

Dean B. Everett,
Jennifer Cornick,
Brigitte Denis,
Claire Chewapreecha,
Nicholas Croucher,
Simon Harris,
Julian Parkhill,
Stephen Gordon,
Enitan D. Carrol,
Neil French

x

Published: September 10, 2012
https://doi.org/10.1371/journal.pone.0044250

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Genomics
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Vaccines
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Antibiotic resistance
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Malawi
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Genome sequencing
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Cloning
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