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A Novel In Vivo siRNA Delivery System Specifically Targeting Liver Cells for Protection of ConA-Induced Fulminant Hepatitis

  • Nan Jiang ,

    * These authors contribute to this work equally.

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada, Liver Transplant Center, The Third Affiliated Hospital of Sun Yat-sen University, Transplantation Research Institute of Sun Yat-sen University, Guangzhou, China

  • Xusheng Zhang ,

    * These authors contribute to this work equally.

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada

  • Xiufen Zheng,

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada

  • Di Chen,

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada

  • Kingsun Siu,

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada

  • Hongmei Wang,

    Affiliation Jiangxi Provincial Institute of Medical Science, and Medical School of Nanchang University, Nanchang, China

  • Thomas E. Ichim,

    Affiliation Medistem Laboratories, San Diego, USA

  • Douglas Quan,

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada

  • Vivian McAlister,

    Affiliation Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada

  • Guihua Chen,

    Affiliation Liver Transplant Center, The Third Affiliated Hospital of Sun Yat-sen University, Transplantation Research Institute of Sun Yat-sen University, Guangzhou, China

  • Wei-Ping Min

    ** Address correspondence and reprint requests to: Dr. Wei-Ping Min (weiping.min@uwo.ca), 339 Windermere Road, University Hospital C9-136, London, Ontario, N6A 5A5, Canada. Tel: 519-663-2985, Fax: 519-663-3295.

    Affiliations Multi-Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada, Department of Surgery, Pathology, and Oncology, University of Western Ontario, London, Ontario, Canada, Liver Transplant Center, The Third Affiliated Hospital of Sun Yat-sen University, Transplantation Research Institute of Sun Yat-sen University, Guangzhou, China

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