XB130 Mediates Cancer Cell Proliferation and Survival through Multiple Signaling Events Downstream of Akt

Atsushi Shiozaki; Grace Shen-Tu; Xiaohui Bai; Daisuke Iitaka; Valentina De Falco; Massimo Santoro; Shaf Keshavjee; Mingyao Liu

doi:10.1371/journal.pone.0043646

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Peer-reviewed

Research Article

XB130 Mediates Cancer Cell Proliferation and Survival through Multiple Signaling Events Downstream of Akt

Atsushi Shiozaki,

Affiliation Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada
⨯
Grace Shen-Tu,

Affiliation Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada
⨯
Xiaohui Bai,

Affiliation Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada
⨯
Daisuke Iitaka,

Affiliation Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada
⨯
Valentina De Falco,

Affiliation Dipartimento di Biologia e Patologia Cellulare e Molecolare, Istituto di Endocrinologia ed Oncologia Sperimentale del CNR ‘G. Salvatore’, Naples, Italy
⨯
Massimo Santoro,

Affiliation Dipartimento di Biologia e Patologia Cellulare e Molecolare, Istituto di Endocrinologia ed Oncologia Sperimentale del CNR ‘G. Salvatore’, Naples, Italy
⨯
Shaf Keshavjee,

Affiliations Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
⨯
Mingyao Liu

* E-mail: mingyao.liu@utoronto.ca

Affiliations Latner Thoracic Surgery Research Laboratories, University Health Network Toronto General Research Institute, Toronto, Ontario, Canada, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
⨯

XB130 Mediates Cancer Cell Proliferation and Survival through Multiple Signaling Events Downstream of Akt

Atsushi Shiozaki,
Grace Shen-Tu,
Xiaohui Bai,
Daisuke Iitaka,
Valentina De Falco,
Massimo Santoro,
Shaf Keshavjee,
Mingyao Liu

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Published: August 23, 2012
https://doi.org/10.1371/journal.pone.0043646

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Small interfering RNA
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Thyroid carcinoma
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Apoptosis
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Lung and intrathoracic tumors
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Phosphorylation
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Tyrosine kinases
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Cancer treatment
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Cell proliferation
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