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Research Article

Both Baseline Clinical Factors and Genetic Polymorphisms Influence the Development of Severe Functional Status in Ankylosing Spondylitis

  • Ruxandra Schiotis mail,

    Elena.Schiotis@umfcluj.ro

    Affiliations: Department of Pharmacology, “Iuliu Hatieganu” University of Medicine and Pharmacy and SCBI- Rheumatology Department, Cluj-Napoca, Romania, Department of Rheumatology, University Hospital “Reina Sofía”/IMIBIC, Córdoba, Spain

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  • Nerea Bartolomé,

    Affiliation: Department of R+D, Progenika Biopharma SA, Derio-Vizcaya, Spain

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  • Alejandra Sánchez,

    Affiliation: Department of Rheumatology, “Puerta de Hierro Majadahonda”, University Hospital, Madrid, Spain

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  • Magdalena Szczypiorska,

    Affiliation: Department of R+D, Progenika Biopharma SA, Derio-Vizcaya, Spain

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  • Jesús Sanz,

    Affiliation: Department of Rheumatology, “Puerta de Hierro Majadahonda”, University Hospital, Madrid, Spain

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  • Eduardo Cuende,

    Affiliation: Department of Rheumatology, University Hospital “Príncipe de Asturias”, Alcalá de Henares, Madrid, Spain

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  • Eduardo Collantes Estevez,

    Affiliation: Department of Rheumatology, University Hospital “Reina Sofía”/IMIBIC, Córdoba, Spain

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  • Antonio Martínez,

    Affiliation: Department of R+D, Progenika Biopharma SA, Derio-Vizcaya, Spain

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  • Diego Tejedor,

    Affiliation: Department of R+D, Progenika Biopharma SA, Derio-Vizcaya, Spain

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  • Marta Artieda,

    Affiliation: Department of R+D, Progenika Biopharma SA, Derio-Vizcaya, Spain

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  • Anca Buzoianu,

    Affiliation: Department of Pharmacology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

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  • Juan Mulero

    Affiliation: Department of Rheumatology, “Puerta de Hierro Majadahonda”, University Hospital, Madrid, Spain

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  • Published: September 12, 2012
  • DOI: 10.1371/journal.pone.0043428

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