IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic Leukemia

• Ilaria Iacobucci ,

  Contributed equally to this work with: Ilaria Iacobucci, Nunzio Iraci

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Nunzio Iraci ,

  Contributed equally to this work with: Ilaria Iacobucci, Nunzio Iraci

  Current address: Brain Repair Centre & Cambridge Stem Cell Initiative, University of Cambridge, Cambridge, United Kingdom

  Affiliation Department of Biology, University of Bologna, Bologna, Italy

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• Monica Messina,

  Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, “Sapienza” University of Rome, Rome, Italy

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• Annalisa Lonetti,

  Affiliation Cellular Signalling Laboratory, Department of Human Anatomy, University of Bologna, Bologna, Italy

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• Sabina Chiaretti,

  Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, “Sapienza” University of Rome, Rome, Italy

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• Emanuele Valli,

  Affiliation Department of Biology, University of Bologna, Bologna, Italy

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• Anna Ferrari,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Cristina Papayannidis,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Francesca Paoloni,

  Affiliation Gruppo Italiano Malattie Ematologiche Maligne dell’Adulto (GIMEMA) Data Center, GIMEMA Foundation, Rome, Italy

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• Antonella Vitale,

  Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, “Sapienza” University of Rome, Rome, Italy

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• Clelia Tiziana Storlazzi,

  Affiliation Department of Genetics and Microbiology, University of Bari, Bari, Italy

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• Emanuela Ottaviani,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Viviana Guadagnuolo,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Sandra Durante,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Marco Vignetti,

  Affiliation Gruppo Italiano Malattie Ematologiche Maligne dell’Adulto (GIMEMA) Data Center, GIMEMA Foundation, Rome, Italy

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• Simona Soverini,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Fabrizio Pane,

  Affiliation CEINGE Biotecnologie Avanzate and Department of Biochemistry and Medical Biotechnology, University of Naples Federico II, Naples, Italy

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• Robin Foà,

  Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, “Sapienza” University of Rome, Rome, Italy

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• Michele Baccarani,

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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• Markus Müschen,

  Affiliation Leukemia Research Program, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, California, United States of America

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• Giovanni Perini,

  Affiliation Department of Biology, University of Bologna, Bologna, Italy

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•  [ ... ],
• Giovanni Martinelli

  * E-mail: giovanni.martinelli2@unibo.it

  Affiliation Department of Hematology and Oncological Sciences “L. and A. Seràgnoli”, S. Orsola Malpighi Hospital, University of Bologna, Bologna, Italy

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