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Research Article

Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88

  • Teri L. Kissner,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Gordon Ruthel,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Shahabuddin Alam,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Enrique Mann,

    Affiliation: Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Dariush Ajami,

    Affiliation: Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Mitra Rebek,

    Affiliation: Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Eileen Larkin,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Stefan Fernandez,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Robert G. Ulrich,

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Sun Ping,

    Affiliation: Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • David S. Waugh,

    Affiliation: Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Julius Rebek Jr,

    Affiliation: Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Kamal U. Saikh mail

    kamal.saikh@amedd.army.mil

    Affiliation: Department of Immunology, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America

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  • Published: July 27, 2012
  • DOI: 10.1371/journal.pone.0040773

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