Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

Marco Genua; Shi-Qiong Xu; Simone Buraschi; Stephen C. Peiper; Leonard G. Gomella; Antonino Belfiore; Renato V. Iozzo; Andrea Morrione

doi:10.1371/journal.pone.0040148

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Research Article

Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

Marco Genua,

Affiliation Endocrine Mechanisms and Hormone Action Program, Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Shi-Qiong Xu,

Affiliation Endocrine Mechanisms and Hormone Action Program, Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Simone Buraschi,

Affiliation Cancer Cell Biology and Signaling Program, Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Stephen C. Peiper,

Affiliation Cancer Cell Biology and Signaling Program, Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Leonard G. Gomella,

Affiliation Endocrine Mechanisms and Hormone Action Program, Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Antonino Belfiore,

Affiliation Endocrinology, Department of Health, University of Catanzaro, Catanzaro, Italy
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Renato V. Iozzo,

Affiliation Cancer Cell Biology and Signaling Program, Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Andrea Morrione

* E-mail: Andrea.Morrione@jefferson.edu

Affiliation Endocrine Mechanisms and Hormone Action Program, Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯

Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

Marco Genua,
Shi-Qiong Xu,
Simone Buraschi,
Stephen C. Peiper,
Leonard G. Gomella,
Antonino Belfiore,
Renato V. Iozzo,
Andrea Morrione

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Published: June 28, 2012
https://doi.org/10.1371/journal.pone.0040148

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