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Research Article

Doxycycline Stabilizes Vulnerable Plaque via Inhibiting Matrix Metalloproteinases and Attenuating Inflammation in Rabbits

  • Mei Dong,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Lin Zhong,

    Affiliation: Yu Huang Ding Hospital, Yantai, Shandong, China

    X
  • Wen Qiang Chen,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Xiao Ping Ji,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Mei Zhang,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Yu Xia Zhao,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Li Li,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Gui Hua Yao,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Peng Fei Zhang,

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Cheng Zhang mail,

    leilybao@163.com (LZ); zhangcheng8003@yahoo.cn (CZ); zhangyun@sdu.edu.cn (YZ)

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Lei Zhang mail,

    leilybao@163.com (LZ); zhangcheng8003@yahoo.cn (CZ); zhangyun@sdu.edu.cn (YZ)

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Yun Zhang mail

    leilybao@163.com (LZ); zhangcheng8003@yahoo.cn (CZ); zhangyun@sdu.edu.cn (YZ)

    Affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Shandong University Qilu Hospital, Jinan, Shandong, China

    X
  • Published: June 21, 2012
  • DOI: 10.1371/journal.pone.0039695

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