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Research Article

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

  • Elisa Lombardo,

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Cindy P. A. A. van Roomen,

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Gijs H. van Puijvelde,

    Affiliation: Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research (LACDR), Leiden University, Leiden, The Netherlands

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  • Roelof Ottenhoff,

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Marco van Eijk,

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Jan Aten,

    Affiliation: Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Johan Kuiper,

    Affiliation: Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research (LACDR), Leiden University, Leiden, The Netherlands

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  • Herman S. Overkleeft,

    Affiliation: Division of Biopharmaceutics, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

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  • Albert K. Groen,

    Affiliation: Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands

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  • Arthur J. Verhoeven,

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Johannes M. F. G. Aerts mail,

    j.m.aerts@amc.uva.nl

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Florence Bietrix

    Affiliation: Departments of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0038520

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