Instrumental Variable Estimation of the Causal Effect of Plasma 25-Hydroxy-Vitamin D on Colorectal Cancer Risk: A Mendelian Randomization Analysis

• Evropi Theodoratou ,

  * E-mail: E.Theodoratou@ed.ac.uk

  Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom

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• Tom Palmer,

  Affiliation MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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• Lina Zgaga,

  Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom, Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia

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• Susan M. Farrington,

  Affiliation MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom

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• Paul McKeigue,

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

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• Farhat V. N. Din,

  Affiliation MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom

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• Albert Tenesa,

  Affiliations MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom, The Roslin Institute, The University of Edinburgh, Easter Bush, Roslin, Scotland

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• George Davey-Smith,

  Affiliation MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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• Malcolm G. Dunlop,

  Affiliation MRC Human Genetics Unit, Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Edinburgh, United Kingdom

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• Harry Campbell

  Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom

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